Título: DE-RISKING METABOLIC, ENVIRONMENTAL AND BEHAVIORAL DETERMINANTS OF OBESITY IN CHILDREN, ADOLESCENTS AND YOUNG ADULTS

Referência | Código da Operação:  GA 101080329

Acrónimo: PAS GRAS

Objetivo temático: PAS GRAS aims to prevent and reverse obesity and associated metabolic complications in four age groups: pre-pubertal children (3-9 yr), adolescents (10-18 yr), young adults (19-25 yr), and adults (25-55).

Área Científica: Public and environmental health 

Síntese do Projeto: PAS GRAS focuses on four main pillars. 1) Develop a personalized risk assessment tool (RAT): an algorithm that will anticipate obesity priming and development in the critical age groups, and identify risk factors for specific complications in subsequent years that will constitute new outcomes for interventional studies. 2) Develop and implement RAT-based personalized interventions by integrating non-pharmacological lifestyle modifications including Mediterranean Diet components alone or with rational pharmacological targeting metabolic and neuroendocrine mechanisms. 3) Inform and engage effectively target groups on obesity causes, risks and intervention by co-production of creative and interactive digital tools (including a simpler version of the RAT) and personalized diet and physical activity programs. 4) Expand and consolidate the PAS GRAS tailor-made campaign across Europe through developing joint programs for health and food/nutrition literacy and physical activity, with healthcare centres, schools, sports clubs, municipalities, and other relevant actors and public authorities. PAS GRAS outcomes will contribute to a long-term 15% decrease in overweight/obesity prevalence in adults and 30% in children/adolescents in the EU until 2050, contributing to a downstream reduction of obesity-associated complications, pharmaceutical and surgical interventions, and to promote Mediterranean Diet as tool for a more nutritious and sustainable future. PAS GRAS is a unique multi- and interdisciplinary research team from 8 countries, including 12 top-level Universities and Research Institutions. Non-academic partners include a civil organization, one company, one patient organization and one Pan-European research Society.

Área de intervenção: Public and environmental health 

Investigador Responsável pelo projeto PAS GRAS: Paulo Jorge Gouveia Simões da Silva Oliveira

Instituições participantes no Projeto:

UNIVERSIDADE DE COIMBRA (UC) – Coordenação do Projeto

UNIVERSITA DEGLI STUDI DI BARI ALDO MORO (UNIBA)

UPPSALA UNIVERSITET (UU)

UNIVERSIDADE NOVA DE LISBOA (UNL)

FUNDACIO EURECAT (EURECAT)

CONSIGLIO NAZIONALE DELLE RICERCHE (CNR)

INSTITUTO POLITECNICO DE VIANA DE CASTELO (IPVC)

TECHNISCHE UNIVERSITAET MUENCHEN (TUM)

INSTYTUT BIOLOGII DOSWIADCZALNEJ IM. M. NENCKIEGO POLSKIEJ AKADEMII NAUK (NENCKI)

INSTITUTO PEDRO NUNES ASSOCIACAO PARA A INOVACAO E DESENVOLVIMENTO EM CIENCIA E TECNOLOGIA (IPN)

THE EUROPEAN SOCIETY FOR CLINICAL INVESTIGATION (ESCI)

MEDIAGNOST GESELLSCHAFT FUR FORSCHUNG UND HERSTELLUNG VON DIAGNOSTIKA GMBH (MEDIAGNOST)

MARTIN-LUTHER-UNIVERSITAT HALLE-WITTENBERG (MLU)

ASSOCIACAO PROTECTORA DOS DIABETICOS DE PORTUGAL (APDP)

AGDCENTRO ASSOCIACAO DE GINASTICA DO CENTRO (AGDCentro)

Instituição Financiadora/Gestora: Comissão Europeia